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Neuralink Wants to Expand Brain Chip Trial to Second Human Patient

The first human patient, Noland Arbaugh, says the chip 'completely changed how I live,' despite a 'thread retraction' issue that will likely need to be addressed before a second trial begins.

 & Michael Kan Principal Reporter

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Elon Musk’s Neuralink is signaling it’s ready to implant its brain chip in a second human patient after more than three months of tests with Noland Arbaugh, the first human subject. 

On Thursday, Musk tweeted: “Neuralink is accepting applications for the second participant. This is our Telepathy cybernetic brain implant that allows you to control your phone and computer just by thinking." His post retweets a Neuralink video intended to recruit eligible users for the second trial; it offers a glimpse of how the brain chip was surgically implanted in Arbaugh in January. 

“It completely changed how I live,” Arbaugh says in the video, which shows how the technology has enabled him to move the cursor on his laptop remotely.  

Neuralink first called for human patients to test the brain chip in September, so the company may already have a database of eligible candidates. In particular, the startup is looking for quadriplegics like Arbaugh or people who’ve lost the ability to use their arms and legs.

The so-called N1 chip reads the user’s brain activity through 64 fine threads that contain 1,024 electrodes. These brain signals are then converted into Bluetooth-based remote commands to control an electronic device, like a mouse cursor. In Arbaugh’s case, the N1 chip has allowed him to control his laptop for eight-plus hours a day, play a variety of video games, and interact on social media. 

“I’m beating my friends in games that, as a quadriplegic, I should not be beating them in,” he told Neuralink last week. 

There have been challenges. Neuralink last week disclosed that an unspecified number of electrode-laced threads attached to the N1 chip had “retracted" from Arbaugh’s brain a month after the surgery. This caused “a net decrease in the number of effective electrodes,” resulting in lower performance for the brain chip before Neuralink made software changes to compensate for the signal loss. 

Since then, Arbaugh’s performance with the N1 chip has surpassed his initial benchmarks. Still, it's unclear why the threads retracted from his brain in the first place, although it appears to be a known problem. Bloomberg recently interviewed Arbaugh and said the threads attached to his brain had shifted more than Neuralink had seen while testing the chip with animals. 

One possible reason is that animal brains tend to be significantly smaller than human brains. Bloomberg also noted that Arbaugh possesses a “thicker-than-average skull,” which could have made it harder for the threads to settle into his brain tissue. What is clear is that Neuralink will no doubt try to address the thread-retraction issue when expanding the brain chip trials to more human patients.

Interested users can sign up for the Neuralink trials by visiting neuralink.com/patient-registry.

About Our Expert

Michael Kan

Michael Kan

Principal Reporter

My Experience

I've been a journalist for over 15 years. I got my start as a schools and cities reporter in Kansas City and joined PCMag in 2017, where I cover satellite internet services, cybersecurity, PC hardware, and more. I'm currently based in San Francisco, but previously spent over five years in China, covering the country's technology sector.

Since 2020, I've covered the launch and explosive growth of SpaceX's Starlink satellite internet service, writing 600+ stories on availability and feature launches, but also the regulatory battles over the expansion of satellite constellations, fights with rival providers like AST SpaceMobile and Amazon, and the effort to expand into satellite-based mobile service. I've combed through FCC filings for the latest news and driven to remote corners of California to test Starlink's cellular service.

I also cover cyber threats, from ransomware gangs to the emergence of AI-based malware. In 2024 and 2025, the FTC forced Avast to pay consumers $16.5 million for secretly harvesting and selling their personal information to third-party clients, as revealed in my joint investigation with Motherboard.

I also cover the PC graphics card market. Pandemic-era shortages led me to camp out in front of a Best Buy to get an RTX 3000. I'm now following how the AI-driven memory shortage is impacting the entire consumer electronics market. I'm always eager to learn more, so please jump in the comments with feedback and send me tips.

The Best Tech I've Had:

  • My first video game console: a Nintendo Famicom
  • I loved my Sega Saturn despite PlayStation's popularity.
  • The iPod Video I received as a gift in college
  • Xbox 360 FTW
  • The Galaxy Nexus was the first smartphone I was proud to own.
  • The PC desktop I built in 2013, which still works to this day.

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